In 1543 the Belgian doctor Andreas Vesalius (1514–64) published "Some Observations on the Dissection of Living Animals" in De Fabrica Humani Corporis. Vesalius hoped to convince other doctors that the study of anatomy was essential to improving medical care. He advocated cutting open living animals to teach students about blood circulation.
During the 1600s the French philosopher and mathematician René Descartes (1596–1650) published some influential essays in which he argued that animals could not think at all. Descartes said that only humans had eternal souls; thus, only humans could reason. He described the human gift of language as proof that humans were philosophically different from animals. Descartes was fascinated with the field of mechanics and extended its ideas to nonhuman animals. He wrote that animals were mechanical things like clocks and therefore could not feel pain. This helped make it socially acceptable to cut open animals while they were still alive for medical and scientific purposes. The process became known as vivisection and was widespread in Europe in the seventeenth and eighteenth centuries.
Literature from this time describes live dogs being nailed to tables in classrooms and dissected to learn about their anatomy. Writers dismissed the cries of the dogs as being similar to the screeching sounds that a piece of machinery makes when it is forcibly taken apart.
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