Library Index :: Death and Dying Reference :: The End of Life: Ethical Considerations - Religious Teachings, Bioethics And Medical Practice, Patient Autonomy, The Desire To Die, The Future Of Medical Ethics

The End of Life: Ethical Considerations - The Desire To Die

AIDS (Acquired Immunodeficiency Syndrome) has directed societal attention to end-of-life decision making because patients infected with HIV (Human Immunodeficiency Virus), which weakens the immune system and leads to AIDS, are faced with decisions about life-prolonging therapies for a disease that as yet has no cure. They know that a number of disorders await them as their immune system is progressively destroyed, including severe wasting, infections, intense pain, blindness, and dementia. Some AIDS patients who do not wish to undergo this protracted dying process or deplete family resources in prolonged care may ask for physicians' aid to hasten death. Likewise, many patients with incurable cancer who are suffering as they die would like their death to be hastened.

Diane E. Meier, et al., surveyed 3,021 physicians younger than 65 years from the 1996 American Medical Association Physician Master File in August, 1996 ("Characteristics of Patients Requesting and Receiving Physician-Assisted Death," Archives of Internal Medicine, vol. 163, no. 13, July 14, 2003). The researchers wanted to determine patient characteristics associated with acts of physician-assisted suicide. Physician-assisted suicide was defined as "writing a prescription or administering a lethal injection with the primary intention of ending the

TABLE 3.1
Characteristics of patients requesting and receiving physician-assisted death, 2003

Number (%)
Total sample* (sample size = 415) Requested lethal prescription (sample size = 215) Requested lethal injection (sample size = 105)
Female sex 155 (39) 74 (35) 39 (39)
White race/ethnicity 346 (89) 183 (90) 87 (86)
Religion
Roman Catholic 55 (17) 23 (14) 16 (20)
Other Christian 199 (61) 103 (62) 55 (68)
Jewish 31 (10) 20 (12) 5 (6)
Other 8 (3) 3 (2) 1 (1)
None 31 (10) 18 (11) 4 (5)
Age
19–45 72 (18) 38 (18) 24 (23)
46–75 226 (56) 125 (59) 52 (50)
>75 103 (26) 49 (23) 28 (27)
Social class
Upper 61 (15) 27 (13) 17 (17)
Middle 285 (71) 149 (71) 74 (73)
Lower 54 (14) 33 (16) 11 (11)
Education
None or elementary school 35 (10) 11 (6) 19 (23)
High school graduate 146 (43) 84 (46) 35 (43)
College graduate 161 (47) 88 (48) 28 (34)
Primary diagnosis
Human immunodeficiency virus 55 (13) 31 (14) 12 (11)
Cancer 194 (47) 100 (47) 45 (43)
Neurologic disease 53 (13) 29 (14) 13 (12)
Other 113 (27) 55 (26) 35 (33)
Experiencing severe pain 156 (38) 71 (33) 40 (39)
Experiencing severe discomfort other than pain 170 (42) 77 (36) 54 (52)
Confused 39 (10) 15 (7) 22 (21)
Depressed at time of request 202 (49) 108 (52) 43 (41)
Experienced recent deterioration in functional status 313 (87) 150 (86) 89 (87)
Dependent for most or all of personal care 217 (53) 96 (45) 71 (68)
Bedridden 173 (42) 62 (29) 68 (65)
Physicians' estimate of life expectancy
<1 month 114 (28) 27 (13) 63 (61)
≥1 month 294 (72) 185 (87) 40 (39)
Duration of patient-physician relationship
<1 month 68 (19) 24 (13) 27 (30)
1 month to 1 year 100 (28) 62 (33) 15 (17)
>1 year 191 (53) 101 (54) 47 (53)
Source of request
Patient or patient with family 361 (89) 201 (95) 72 (71)
Family only 46 (11) 11 (5) 30 (29)
Type of request
Lethal prescription 215 (52) 215 (100) 0
Lethal injection 105 (25) 0 105 (100)
Either prescription or injection 95 (23) 0 0
*Total sample included 215 who requested a lethal prescription, 105 who requested a lethal injection, and 95 who made a nonspecific request.
SOURCE: Diane E. Meier, et al., "Table 1. Characteristics of Patients in Sample: Overall and by Type of Request," in "Characteristics of Patients Requesting and Receiving Physician-Assisted Death," Archives of Internal Medicine,vol. 163, July 14, 2003

patient's life." Of the 3,021 physicians surveyed, 1,902 (63 percent) responded.

Table 3.1 contains descriptions of physicians' most recent patient and family requests for assistance in dying. More than half the patients described were male (61 percent) and most of the patients were white (89 percent). Nearly half (47 percent) of those in the sample were college graduates, and nearly half (47 percent) had cancer as a primary diagnosis. Infection with HIV was the primary diagnosis for 13 percent. Many (38 percent) were experiencing severe pain and 42 percent were experiencing severe discomfort other than pain. About half (49 percent) were depressed (as diagnosed by their physicians) at the time of their request, were dependent for most or all of their personal care (53 percent), and were bedridden (42 percent). Nearly three-quarters of those in the sample (72 percent) were expected to live one month or more, while the remaining 28 percent were expected to live less than a month. About half of those in the sample requested a lethal prescription (52 percent) to hasten their death.

Meier and her colleagues analyzed their survey data to identify factors associated with a physician honoring a request for aid in dying. Table 3.2 is an analysis of data from physicians who did honor such requests. It shows those factors that significantly increased the likelihood that a physician would honor a request for aid in dying. These factors are considered predictors of request-honoring behavior, and the column "odds ratio" shows the likelihood of a factor (compared to other listed factors) influencing a physician to comply with the request.

The factor most likely to predict that a physician would honor a request for aid in dying was the specificity of the request. (See Table 3.2.) That is, specific requests for assistance, such as requests for lethal prescriptions or lethal injections, were predictors of requests being honored, while nonspecific requests were not predictors of requests being honored. Other predictors of physicians' decisions to honor patients' requests for assistance in dying included severe pain, severe discomfort other than pain, and a life expectancy of less than one month. Some patients were believed to be depressed at the time of their request, and although physicians did honor some of these requests, they were less likely to honor a request if they knew the patient was depressed.

Further analysis of the survey data identified factors associated with a physician honoring a request for aid in dying for patients requesting a lethal injection and those requesting a prescription for a lethal dose of medication. (See Table 3.3.) For patients requesting a lethal injection, those with severe physical discomfort other than pain and patients with a life expectancy of less than one month were significantly more likely to have their request honored than patients without these characteristics. For patients requesting a prescription for a lethal dose of medication, those with severe pain and severe physical discomfort other than pain were significantly more likely to have their request honored than patients without these characteristics. In both groups, patients who were

TABLE 3.2
Independent patient-related factors associated with physicians honoring a request for hastened death, 20031

Odds ratio
Type of request2
Prescription 43
Injection 106
Patient depressed at time of request 0.2
Patient in severe pain 2.4
Patient in severe discomfort other than pain 6.5
Patient life expectancy <1 month 4.3
1Responses from physicians who stated that they would not honor a patient's request for assistance in dying under any circumstances were excluded from the analysis.
2Reference category was nonspecific request for prescription or injection.
SOURCE: Diane E. Meier, et al., "Table 2. Independent Patient-Related Factors Associated with Physicians Honoring a Request for a Hastened Death," Archives of Internal Medicine, vol. 163, July 14, 2003

depressed at the time of their requests were less likely to have their requests honored than those who were not depressed.

User Comments Add a comment…